Eurostar will begin the new services on May 1 2015, with the £89 price being for a return to Lyon, with r eturns to Marseille and Avignon starting at £99.
Passengers travelling from southern France back to the UK can board their train without the need to arrive 30 minutes before departure. But they will have to go through check-in, security and immigration checks at Lille in northern France where they will have to leave the train before continuing their journey.
The London to Lyon best journey time will be four hours 41mins, with Avignon five hours 49 minutes and Marseille six hours 27 minutes.
Eurostar commercial director Nick Mercer said: “Brits have a long-standing love affair with the south of France, and our new service brings the gastronomy, culture and art from the region closer to the UK.”